定制人工骨，为治疗我的疾病找到了答案

骨缺损及融合治疗中心

Mr. I am not a failure, although I live cautiously because of my short stature.

Mr. Accidents happen again, causing fractures due to unexpected car accidents.

Mr. I was alienated because my deformed limbs caused me physical and mental pain.

Thanks to high technology in modern medicine, such as Ilizarov technology, they can return to life with a smile

Ilizarov technology is widely used in bone defects and related rare bone diseases caused by musculoskeletal problems. In principle, the normal bone is cut off near the diseased bone and fixed firmly with an external fixator, allowing 1mm of new bone to form every day.

However, this requires patience, as it takes 30 days for 1cm to grow normally.

And there are also complications, such as delayed healing or non-union requiring re-operation to implant artificial bone to promote osteogenesis, and pin site infections requiring antibiotics.

Currently, Korea University Medical Center is working hard to apply for a "fracture treatment package product" to clinical practice. This includes external fixation devices, products that promote bone formation and bone healing, as well as a series of products that prevent wound adhesion and artificial bone to promote complete recovery from fracture and bone defect diseases.

Currently, the medical center especially emphasizes accelerating the technological development and research of artificial bone manufacturing, because this is the core of treatment.

A technique for manufacturing artificial bone named by Korea University Medical Center is "Theoretical method for manufacturing artificial bone with antibiotics and bone formation induction and antibacterial activity".

Attempts to reduce the failure rate of implants caused by bacterial infections and promote bone formation to shorten treatment time.

Polymethyl methacrylate, bone cement (PMMA) has the disadvantages of being difficult to control the release of antibiotics and requiring a second surgery to remove it.

Allograft bone grafts obtained from cadavers, etc., require re-operation due to slower osteogenesis.

Autologous bone grafts have the risk of postoperative pain and infection complications because bone tissue is taken from another part of the patient's own normal body.

The artificial bone manufacturing technology of Korea University Medical Center provides the advantages of artificial bone

Inject antibiotics and bone-forming growth factor BMP-2. The surface is sequentially treated with dopamine and heparin.

Bacterial infections can be prevented due to the long-term continuous release of antibiotics during and after implantation, so the implantation failure rate is significantly reduced.

At the same time, BMP-2 is continuously released between artificial bone and bone tissue to promote bone fusion and bone regeneration, promote osteoblast differentiation, and promote bone formation. In this way, the treatment cycle can be shortened to 10 days.

In addition, artificial bone can be customized for each patient, and the success rate of implantation is increased, which reduces the financial burden of reoperation

Currently, 3D bioprinting technology, stem cells and artificial bone surface coating technology are also being developed for large-scale production of artificial bone.

The BMP-2 (growth factor) market led by the United States has a huge economic value of 1 trillion won in the US market alone.

Due to the aging population and the increasing incidence of fractures and bone defects, the artificial bone market will develop rapidly.

In the current situation, the "fracture treatment package product" promoted by the Bone Disease and Bone Defect Fusion Treatment Center of Korea University Medical Center will play a leading role in the Korean medical market.